Surekha was born 1945 in Dehradun, Uttarakhand. Her father was in the Air Force and her mother was a teacher. Her grandfather was a doctor. She was married to Hemant Rege and she has a son who lives in Delhi. He is in his late twenties. He is an artiste, a self-taught painter. Her husband was involved in production work. Her husband passed away in 2008.
Surekha Sikri graduated from National School of Drama (NSD) in 1968, and worked with the NSD Repertory Company for over a decade before shifting base to Mumbai.
She has won the National Film Award for Best Supporting Actress twice, for her role in Tamas in 1988 and for Mammo in 1995.Surekha Sikri was the recipient of 1989 Sangeet Natak Akademi Award.In Dec 2008, she was awarded “Best actress in negative role” for the serial Balika Vadhu (Colors TV), in the IDEA ITA Awards 2008.Due to balika vadhu she became the negative diva of telly wood.