Madhu Shalini is an Indian film actress and model, who has appeared in Telugu and Tamil language films. She has previously worked as a television anchor as well.She has been signed by Ram Gopal Varma for his upcoming directorial Department, which would mark her debut in Bollywood and feature her as a female gangster alongside Amitabh Bachchan, Sanjay Dutt and Rana Daggubati.

Madhu Shalini was born on 21 July 1989 in Hyderabad.Her father is a businessman and her mother is an advocate.She also learned Kuchipudi, before taking part in a beauty contest, which she incidentally won and which paved her way for a modelling career. After working as a television anchor for a short while, she soon ventured into film business, turning an actress.

She made her feature film debut with the 2005 Telugu film Naa Pranam Kante Ekkuva directed by music composer Shashi Preetam.

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